WebPhase II trial of AV-GBM-1: dendritic cell vaccine pulsed with lysate enriched for autologous tumor-initiating cell antigens in the treatment of patients with newly diagnosed … WebDec 29, 2024 · AIVITA's glioblastoma Phase 2 single-arm study is active and completed treating 57 patients with the tumor-initiating cell-targeting immunotherapy, AV-GBM-1. In a final analysis of progression-free survival, patients treated with AV-GBM-1 had a 38% increase in progression-free survival as compared to Stupp's standard of care.
Immunotherapy Is on the Rise in Glioblastoma Treatment
WebDec 17, 2024 · Four vaccines/ immunotherapy candidates including VBI-1901 (VBI Vaccines), AV-GBM-1 (Aivita Biomedical) and ITI-1000 (Immunomic Therapeutics), and Tasadenoturev (DNAtrix) are also demonstrating ... WebJun 15, 2024 · This novel immunotherapy is administered subcutaneously. Altogether, AV-GBM-1 works to target and eliminate multiple antigens to prevent glioblastoma growth or progression. 57 patients enrolled in the clinical trial. During the trial, patients received 8 AV-GBM-1 doses over a 6-month period. definition of body mass index
Randomized Trial of AV-GBM-1 vs Control as Adjunctive
WebNov 17, 2024 · AV-GBM-1 is a novel immunotherapy consisting of autologous dendritic cells loaded with autologous tumor antigens derived from self-renewing tumor-initiating cells. The treatment is administered in ... WebJul 2, 2024 · About AIVITA Biomedical. AIVITA Biomedical, Inc. is a personalized vaccine company designing COVID-19 and immuno-oncology vaccine therapies that target the … WebClinical & Commercial Programs. AIVITA’s lead therapeutic focus is a patient-specific immunotherapy for the treatment of advanced cancers, currently being investigated in … feline rhinotracheitis shot