Capg macrophage

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August undefined, 2024

WebCapG (gelsolin-like actin-capping protein) is a member of the gelsolin superfamily proteins, which regulates actin filament length by capping or severing filaments. Studies have shown a role for CapG in regulating cell motility. The expression of CapG is upregulated under hypoxia and in turn increases the motility of cells. WebThe ELISA kits listed below target CAPG, the symbol for the human gene, capping actin protein, gelsolin like, and a member of the Villin/gelsolin family. The protein encoded by CAPG has a predicted amino acid length of 348, a mass of 38.5 kDa, and a cytoplasmic and nuclear subcellular localization. There are currently 2 reported isoforms.

Macrophage-capping protein - Wikipedia

WebSep 6, 2024 · Abstract and Figures To investigate the role of macrophage-capping protein (CapG) in the development and progression of colorectal carcinoma (CRC), … WebMar 29, 2024 · CapG was up-regulated in the tumor tissues of patients with lymph node metastasis (LNM), whereas it showed an equivalent expression level between … bozeman genetic recombination

Anti-CapG Antibody (H-9) SCBT - Santa Cruz Biotechnology

WebMacrophage‑capping protein (CapG) is a newly characterized oncogene involved in several types of cancer. However, the expression patterns and biological mechanisms of CapG in clear cell renal... WebCAPG is involved in macrophage function. CAPG is involved in regulating cytoplasmic and/or nuclear structures via possible interactions with actin. CAPG binds DNA. CAPG lacks a nuclear export sequence present in structurally related proteins. CAPG is a tumor suppressor protein that plays a role in the tumorigenic progression of certain cancers. WebDec 17, 2024 · These cells express the marker genes CD9 and TREM2, a tumor suppressor in hepatocellular carcinoma (Tang et al, 2024 ), as well as the markers CAPG and GPNMB. GSEA analysis of Subramanian et al ( 2005) SAM genes resulted in a significant enrichment of apical junction genes and the complement system. gymnastics class near me for kids

Comparisons of CapG and gelsolin-null macrophages - PMC

WebJan 12, 2016 · CAPG and GIPC1: Breast Cancer Biomarkers for Bone Metastasis Development and Treatment The composite biomarker, CAPG and GIPC1 in primary … WebCapG, also designated Actin-regulatory protein and macrophage-capping protein, is a macrophage-specific protein that reversibly blocks the barbed ends of Actin filaments, but does not sever preformed ones. The interactions of CapG with Actin may be important in the regulation of nuclear and cytoplasmic structures. gymnastics classes reno nvWebCAPG is involved in macrophage function. CAPG is involved in regulating cytoplasmic and/or nuclear structures via possible interactions with actin. CAPG binds DNA. CAPG lacks a nuclear export sequence present in structurally related proteins. CAPG is a tumor suppressor protein that plays a role in the tumorigenic progression of certain cancers. gymnastics class west lothian

"WebAug 8, 2001 · Our observations indicate that CapG is required for receptor-mediated ruffling, and that it is a major functional component of macrophage phagocytosis. These primary effects on macrophage motile function suggest that CapG may be a useful target for the regulation of macrophage-mediated inflammatory responses. " - Capg macrophage

Capg macrophage

CAPG enhances breast cancer metastasis by competing with …

WebMacrophage capping protein (CAPG), also known as capping protein (actin filament) or gelsolin-like, is a relatively small actin filament end-capping protein (38.5 kDa) of gelsolin superfamily. CAPG localizes in both nucleus and cytoplasm of the cell [3]. Its function in the cytoplasm is involved in capping the ends of actin filaments and WebMay 23, 2024 · CAPG is an important actin-binding protein, which was first found in human alveolar macrophages, and it is Ca 2+ dependent actin-binding protein which is composed of 348 amino acids. It regulates the length of actin by capping and cutting microfilaments to promote the cross-linking of actin and the reorganization of the cytoskeleton ( 15 ).

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WebCAPG protein (human) - STRING interaction network Viewers Legend Settings Analysis Exports Clusters More Less Nodes: Network nodes represent proteins splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus. Node Color colored nodes: WebFeb 9, 2024 · CAPG expression was positively correlated with infiltrating levels of regulatory T cells (Tregs), tumor-associated macrophages (TAMs), and exhausted T cells (Texs) …

WebMar 21, 2024 · CAPG (Capping Actin Protein, Gelsolin Like) is a Protein Coding gene. Among its related pathways are TYROBP causal network in microglia . Gene Ontology (GO) annotations related to this gene include actin binding and protein-containing complex … WebCalcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage …

WebFeb 9, 2024 · The Capping Actin Protein, Gelsolin-Like (CAPG) gene encodes an actin-regulatory protein, which plays important roles in tumor progression and immune regulation. This study is aimed at identifying the potential therapeutic and prognostic roles of CAPGin ovarian cancer. WebImmunohistochemistry-Paraffin: CapG Antibody [NBP1-90214] - Staining of human lymph node shows moderate to strong cytoplasmic positivity in macrophages. Immunohistochemistry-Paraffin: CapG Antibody [NBP1-90214] - Staining of human skeletal muscle shows no positivity in myocytes as expected.

Web采用免疫组织化学法检测巨噬细胞加帽蛋白G(CapG)、酪氨酸激酶受体B(TrkB)、同源盒基因转录因子1(Prox-1)、基质金属蛋白酶2(MMP-2)、血管内皮生长因子C(VEGF-C)和血管内皮生长因子受体3(VEGFR3)在胃癌术前病理组织中的表达。

WebMacrophage-capping protein (CAPG) has been shown to promote cancer cell metastasis, although the mechanism remains poorly understood. Methods: Breast cancer (BC) tissue microarray was used to test the role of CAPG in the prognosis of BC patients. Xenograft mice model was used to validate the metastasis promotion role of CAPG in vivo. bozeman ghost tourWebMacrophage‑capping protein (CapG) is a newly characterized oncogene involved in several types of cancer. However, the expression patterns and biological mechanisms of CapG in clear cell renal... gymnastics class for girls near meWebJul 3, 2024 · CAPG macrophage capping protein cDNA complementary DNA CL corpus luteum DEGs differentially expressed genes DMEM Dulbecco's modified eagle medium DMSO dimethyl sulfoxide DPBS Dulbecco's phosphate-buffered solution dsDNA double stranded deoxyribonucleic acid dTTP deoxythymidine triphosphate dUTP deoxyuridine … bozeman gift cards