WebOct 2, 2010 · The treatment of malignant middle cerebral artery infarction (mMCAI) has been problematic for many years [1–4].The three European trials (DECIMAL [], DESTINY [], and HAMLET []) as well as their pooled analysis [] provided evidence that decompressive hemicraniectomy (DH) results in a dramatic reduction of mortality compared to patients … WebJan 1, 2024 · After the pooled analysis of these trials 5 showed functional improvement in patients undergoing DHC, DESTINY II analyzed the outcomes in patients ≥60 years old. 7 Hemicraniectomy improved mortality, although only 6% of patients achieved mRS score 3, and no patients achieved mRS score 0–2. Compared with patients younger than 60 …
DESTINY II: Benefit of Surgery for Stroke With Swelling
WebMar 21, 2014 · DESTINY II was a multicenter randomized controlled trial (RCT) of decompressive hemicraniectomy surgery vs. medical care for patients age >60 with large hemispheric ischemic strokes with brain … WebDec 19, 2024 · The initial three randomised controlled trials (DECIMAL , HAMLET and DESTINY ) considered individually or with pooled patient data analysis demonstrated that hemicraniectomy was superior to medical management alone in both survival and functional outcome measured using the modified Rankin score (mRS) where good … grammy silk sonic opening
Evidence review for decompressive hemicraniectomy
WebThere are multiple international randomized controlled trials evaluating the outcomes of DC in the setting of space-occupying malignant infarction. Three European randomized control trials, the Dutch HAMLET trial, the German DESTINY trial, and the French DECIMAL trial, compared hemicraniectomy to standard medical treatment [4, 15, 26, 38]. All ... WebMar 1, 2011 · The German Decompressive Surgery for the Treatment of Malignant Infarction of the Middle Cerebral Artery (DESTINY) trial randomized 32 patients, aged 18–60 years, with the primary endpoint defined as mortality at 30 days. ... Findlay JM. Hemicraniectomy for massive middle cerebral artery infarction: a review. Can J Neurol Sci. 2008;35:544 ... WebHemicraniectomy increased survival without severe disability among patients 61 years of age or older with a malignant middle-cerebral-artery infarction. The majority of survivors … chinasworld.de rosenthal