site stats

Human autophagy modulator database

WebJan 4, 2024 · Human Autophagy Database, and the Autophagy Regulatory Network. The Autophagy database comprehensively provides information on the ATG proteins across … WebMar 2, 2024 · Autophagy, an evolutionarily conserved process, is intricately involved in many aspects of human health and a variety of human diseases, including cancer. Discovery of small-molecule autophagy modulators with potent anticancer effect would be of great significance.

Index-Home-Human Autophagy Moderator Database …

WebNov 2, 2024 · Abstract. Autophagy is a highly dynamic and multi-step process, regulated by many functional protein units. Here, we have built up a comprehensive and up-to-date … WebApr 10, 2024 · Main. Macro-autophagy (hereafter termed ‘autophagy’) encapsulates large intracellular cargos in a double-membrane structure named the autophagosome 1, 2. Upon fusion of the autophagosome with ... compass of indiana https://florentinta.com

AutophagySMDB: a curated database of small molecules …

http://hamdb.scbdd.com/ WebAug 9, 2024 · AMTDB: A comprehensive database of autophagic modulators for anti-tumor drug discovery Introduction. Autophagy is the process by which cells clean up … WebJul 31, 2024 · View. Show abstract. ... 22 November 2024) is a manually curated database containing information on 841 chemicals, 132 microRNAs and 796 proteins, related to the … compass of marksville

Autophagy and Tumor Database: ATdb, a novel database …

Category:IJMS Free Full-Text Natural Compounds Targeting the Autophagy ...

Tags:Human autophagy modulator database

Human autophagy modulator database

The Autophagy Database: an all-inclusive information resource on ...

WebMar 22, 2024 · Damage-regulated autophagy modulator 1 (DRAM1) induces autophagy and is necessary for p53-mediated apoptosis. However, the signalling pathways regulated by DRAM1 are not fully understood. ... human cancer cells Hela, SW480, and HCT116 were transfected with the FLAG-DRAM1 plasmid and phosphorylated rpS6 and rpS6 were … WebApr 15, 2024 · Autophagy is a highly conserved intracellular degradation pathway by which misfolded proteins or damaged organelles are delivered in a double-membrane vacuolar vesicle and finally degraded by lysosomes. The risk of colorectal cancer (CRC) is high, and there is growing evidence that autophagy plays a critical role in regulating the initiation …

Human autophagy modulator database

Did you know?

WebAutophagy is an important homeostatic cellular recycling mechanism responsible for degrading unnecessary or dysfunctional cellular organelles and proteins in all living cells. … WebJul 31, 2024 · Europe PMC is an archive of life sciences journal literature.

WebDec 1, 2024 · Autophagy is an important clearance system for cellular waste, including toxic protein aggregates. It plays an important role in the central nervous system and is critical for the health and survival of neurons (Nikoletopoulou et al., 2015 ). WebResults and Discussion Setting up of a human autophagy data- base (HADb). A comprehensive data- base called HADb was implemented by integrating genomic data and sequence analysis features of the human genes involved in or related to autophagy. HADb is available, free, at www.auto- phagy.lu.

WebHAMdb: a database of human autophagy modulators with specific pathway and disease information. Ning Ning Wang, Jie Dong, Lin Zhang, Defang Ouyang, Yan Cheng, Alex F. Chen, Ai Ping Lu, Dong Sheng Cao * * Corresponding author for this work. Institute for Advancing Translational Medicine in Bone and Joint Diseases; WebNov 1, 2024 · Autophagy is a highly dynamic and multi-step process, regulated by many functional protein units. Here, we have built up a comprehensive and up-to-date annotated gene list for the autophagy...

WebJul 31, 2024 · 8 Institute for Advancing Translational Medicine in Bone and Joint Diseases, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, SAR, People's …

http://hamdb.scbdd.com/home/browse/ compass of lafayettehttp://hamdb.scbdd.com/home/download/ ebc brake discs for motorcyclesWebSep 2, 2024 · Human Autophagy Modulator Database. AR-DEGs: Autophagy-related differentially expressed genes. GO: Gene ontology. DSigDB: Drug Signatures database. … ebc boxing frankfurt