WebDec 26, 2014 · The data obtained show that in HeLa cells paclitaxel acts by blocking MEK and consequently, inactivating ERK1/2 and inhibiting phosphorylation of BAD at serine 112 through RSK. This releases BAD ... WebAug 13, 2014 · We apply the method of differential electrical impedance spectroscopy to treated HeLa cells in order to elucidate the changes in electrical properties compared with non-treated cells. We found that our microfluidic system was able to distinguish between treated and non-treated cells.
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WebApr 9, 2024 · Cervical cancer (CC) is one of the most common female malignancies in the world. Although paclitaxel (PTX) is a critical chemotherapy agent for the treatment of CC, its treatment outcome is limited by the development of drug resistance. The present study aims to define the role of long non-coding RNA (lncRNA) LINC00511 in the progression of CC … WebSep 16, 2005 · HeLa cells were treated with paclitaxel for 24 hours followed by a 24-hour exposure to NU6140 or purvalanol A, and the opposite sequence was also tested. As shown in Table 1, both CDK inhibitors cooperated with paclitaxel to inhibit clonogenic cell survival. costruzioni primitive video
Generating Paclitaxel-Resistant in Cervical Cancer HeLa Cell …
WebFeb 4, 2014 · HeLa cells were used as negative control. Dose-response activation of AMPK, phosphorylation of ACC and Raptor in LKB1 null HeLa (left) and DU145 (right) cells, after 30-min incubation with MT 63–78, at indicated concentrations. AMPK activity in HeLa cells treated with CaMKKβ inhibitor STO-609. WebFigure 2D indicates the paclitaxel content in MP-PTX extracted from 4 × 10 7 HeLa cells treated with different concentrations of paclitaxel. UV-irradiated HeLa cells were … WebMay 15, 2006 · Data propose that paclitaxel-induced HeLa cell death accompanies the induction of TB4 expression as an early response to paclitaxel treatment and the stably overexpressed TB4 might play a role to reveal drug resistance, at least, to paclitaxel. It is required to clarify the mechanism of action on the induction of paclitaxel-resistance by TB4. mac video editing apps