Tfrc蛋白大小
WebTransferrin receptor 1 (TfR1), encoded by the TFRC gene, is the gatekeeper of cellular iron uptake for cells. A variety of molecular mechanisms are at work to tightly regulate TfR1 expression, and abnormal TfR1 expression has been associated with various diseases. In the current study, to determine … Web6 Apr 2024 · 转铁蛋白受体的结构及功能.doc.doc. 要】人体细胞的正常代谢需要铁,其中转铁蛋白受体(TfR)参与铁的吸收和调节。. TfR在所有细胞都呈低表达,在增殖活跃的细胞高表达。. 与正常组织相比,肿瘤组织TfR的表达显著增高,因此,TfR成为肿瘤靶向治疗的研究热 …
Tfrc蛋白大小
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Web24 Jan 2024 · Transferrin receptor 1 (Tfr1) mediates uptake of circulating transferrin-bound iron to developing erythroid cells and other cell types. Its critical physiological function is highlighted by the embryonic lethal phenotype of Tfr1-knockout (Tfrc −/−) mice and the pathologies of several tissue-specific knockouts.We generated Tfrc Alb-Cre mice bearing … WebThe Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
Web30 May 2006 · When dietary levels of stearate (C18:0) are high, TFRC stearoylation inhibits activation of the JNK pathway and thus degradation of the mitofusin MFN2 (PubMed:26214738). By similarity. 3 publications (Microbial infection) Acts as a receptor for new-world arenaviruses: Guanarito, Junin and Machupo virus. 2 publications. Web蛋白分子量计算. 蛋白分子量计算工具:根据输入的一条或多条蛋白序列计算蛋白分子量,并可以选择添加短序列标签至蛋白序列上。. 在下面的文本框中输入原始序列或者一条或者 …
Web21 Mar 2024 · TFRC (Transferrin Receptor) is a Protein Coding gene. Diseases associated with TFRC include Immunodeficiency 46 and Combined Immunodeficiency.Among its related pathways are Signaling by Rho GTPases and RHOC GTPase cycle.Gene Ontology (GO) annotations related to this gene include RNA binding and double-stranded RNA … WebSrc Antibody #2108. Src Antibody. #2108. 对 A-431 细胞提取物 Src 进行免疫沉淀分析。. 泳道 1 为 10% input,泳道 2 为 Normal Rabbit IgG #2729,泳道 3 为 Src Antibody。. 使用 …
Web13 May 2024 · TFRC-mediated iron import is at the center of this novel feed-forward loop to facilitate colonic epithelial cell survival. Mechanistically, disruption of TFRC led to a …
WebProteintech matches its’ customers’ dedication to research by providing high-quality antibodies, ELISA kits and proteins that contribute to reproducible results. Learn more here. software engineering background imagesWeb6 Sep 2024 · The TFRC gene encodes the transferrin receptor, which is important for cellular iron uptake. Circulating apotransferrin (TF; 190000) binds 2 Fe (3+) ions to form holotransferrin, which binds to TFRC. The TFRC-holotransferrin complex is internalized by receptor-mediated endocytosis (summary by Jabara et al., 2016 ). software engineering architecture patternsWeb5 Aug 2024 · 3.4 TFRC突变引起的先天性免疫缺陷 TfR1是哺乳动物发育必不可少的,Tfrc敲除小鼠显示胎死。然而,近期,发现了两个含有TFRC错义突变(Y20H)的家族。 然而, … slow edge