WebbNational Institutes of Health-funded PsychENCODE project and the study of chromatin remodeling complexes have converged to provide a clearer understanding of the organization of the neurogenic epigenome in humans. Neuropsychiatric diseases, including schizophrenia, bipolar spectrum disorder, autism spectrum disorder, attention deficit … WebbTrio-based whole-genome sequencing identified the role of chromatin modification in OCD pathology.
The PsychENCODE project — Mayo Clinic
Webb14 apr. 2024 · [SMR] summary-based mendelian randomization. GitHub Gist: instantly share code, notes, and snippets. Webb30 jan. 2024 · Second, in the PsychENCODE database, to replicate the brain eQTL results of SMR analysis, we used the cis-eQTL data in the prefrontal cortex from the PsychENCODE project (n = 1387) . The eQTL analyses of PsychENCODE were performed including100 hidden covariate factors as covariates. fka twigs and rob pattinson
Liz LaMarca, PhD - Scientist II - Singular Genomics
WebbSee also: Won et al. 2016, Chromosome conformation elucidates regulatory relationships in developing human brain, Nature. De la Torre-Ubieta et al. 2024, The Dynamic Landscape … Webb16 maj 2024 · Schahram Akbarian discusses his work in neuropsychiatric epigenetics, the importance of understanding the 3D organization of the genome and his role in the … Webb26 maj 2024 · Understanding cell-type-specific gene regulatory mechanisms from genetic variants to diseases remains challenging. To address this, we developed a computational pipeline, scGRNom (single-cell Gene Regulatory Network prediction from multi-omics), to predict cell-type disease genes and regulatory networks including transcription factors … fka twigs article